Pastitsio - Baked Pasta with Meat and Bechamel Topping (Greek Lasagna) Pastitsio, from Italian "pasticcio" , sometimes spelled pastichio, is a Greek and Mediterranean baked pasta dish including ground beef and béchamel sauce in its best-known form. The word pastitsio (pa-STEE-tsee-oh) translates to "messy kitchen" in Greek. The Greek word pastitsio derives from the